Anti-PRDX3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PRDX3 Polyclonal Antibody

品牌:solarbio | 货号:K003581P

英文名称 Anti-PRDX3 Polyclonal Antibody
宿主 Rabbit
别名 AOP-1;AOP1;HBC189;MER5;PRO1748;SP-22;prx-III
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 28kDa
Gene ID 10935
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human PRDX3
性状 液体
Public Immunogen Range A synthetic peptide of human PRDX3
Subcellular Locations Mitochondrion
Swiss Prot P30048
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.