Anti-ADAMTS5 Polyclonal Antibody
品牌：solarbio | 货号：K007385P
| 英文名称 | Anti-ADAMTS5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ADMP-2;ADAM-TS5;ADAMTS-5;ADAMTS11;ADAM-TS 5;ADAMTS-11;ADAM-TS 11 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 102kDa |
| Gene ID | 11096 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ADAMTS5 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ADAMTS5 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9UNA0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. |