Anti-ITGA6 Polyclonal Antibody
品牌：solarbio | 货号：K003638P
| 英文名称 | Anti-ITGA6 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD49f;ITGA6B;VLA-6 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 127kDa |
| Gene ID | 3655 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ITGA6 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ITGA6 |
| Subcellular Locations | Cell membrane Lipid-anchor Single-pass type I membrane protein |
| Swiss Prot | P23229 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. |