Anti-LITAF Polyclonal Antibody
品牌:solarbio | 货号:K004017P
英文名称 |
Anti-LITAF Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PIG7;SIMPLE;TP53I7 |
应用 |
WB IHC IP |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IP 1:50-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
17kDa |
Gene ID |
9516 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human LITAF |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human LITAF |
Subcellular Locations |
Cytoplasmic side Lysosome membrane Peripheral membrane protein |
Swiss Prot |
Q99732 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget’s disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. |