Anti-NTRK1 Polyclonal Antibody
品牌：solarbio | 货号：K007565P
| 英文名称 | Anti-NTRK1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MTC;TRK;TRK1;TRKA;Trk-A;p140-TrkA |
| 应用 | IHC |
| 稀释比例 | IHC 1:100-300. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 87/84/77kDa |
| Gene ID | 4914 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human NTRK1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human NTRK1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P04629 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |