Anti-PPL Polyclonal Antibody
品牌：solarbio | 货号：K004888P
| 英文名称 | Anti-PPL Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PPL |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 205kDa |
| Gene ID | 5493 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PPL |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PPL |
| Subcellular Locations | Cell junction Cell membrane Cytoplasm Mitochondrion Nucleus cytoskeleton desmosome |
| Swiss Prot | O60437 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. |