Anti-PTPRN Polyclonal Antibody
品牌：solarbio | 货号：K004496P
| 英文名称 | Anti-PTPRN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IA-2;IA-2/PTP;IA2;ICA512;R-PTP-N |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 106kDa |
| Gene ID | 5798 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PTPRN |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PTPRN |
| Subcellular Locations | Cell junction Cell membrane Cell projection Cytoplasmic vesicle Endosome Membrane Perikaryon Single-pass type I membrane protein axon secretory vesicle membrane synapse |
| Swiss Prot | Q16849 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants. |