Anti-ADSL Polyclonal Antibody
品牌：solarbio | 货号：K004403P
| 英文名称 | Anti-ADSL Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AMPS;ASASE;ASL |
| 应用 | WB IF IP |
| 稀释比例 | WB 1:500-2000. IF 1:20-100. IP 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 55kDa |
| Gene ID | 158 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ADSL |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ADSL |
| Subcellular Locations | Cytosol |
| Swiss Prot | P30566 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. |