Anti-HDAC5 Polyclonal Antibody
品牌：solarbio | 货号：K005072P
| 英文名称 | Anti-HDAC5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HD5;NY-CO-9 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:20-50. |
| 交叉反应 | Human |
| 蛋白分子量 | 122kDa |
| Gene ID | 10014 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human HDAC5 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human HDAC5 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9UQL6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. |