Anti-MASP1 Polyclonal Antibody
品牌：solarbio | 货号：K008185P
| 英文名称 | Anti-MASP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | 3MC1;MAP1;MASP;RaRF;CRARF;MASP3;MAp44;PRSS5;CRARF1 |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 79kDa |
| Gene ID | 5648 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MASP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MASP1 |
| Swiss Prot | P48740 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants. |