Anti-DNMT3A Polyclonal Antibody
品牌:solarbio | 货号:K006733P
英文名称 |
Anti-DNMT3A Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DNMT3A2;M.HsaIIIA |
应用 |
IHC |
稀释比例 |
IHC 1:100-300. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
102kDa |
Gene ID |
1788 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human DNMT3A |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human DNMT3A |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
Q9Y6K1 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. |