Anti-Phospho-MDM2-S166 Polyclonal Antibody
品牌：solarbio | 货号：K006196P
| 英文名称 | Anti-Phospho-MDM2-S166 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ACTFS;HDMX;hdm2 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-1000. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 55kDa |
| Gene ID | 4193 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S166 of human MDM2 |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding S166 of human MDM2 |
| Subcellular Locations | Cytoplasm Nucleus nucleolus nucleoplasm |
| Swiss Prot | Q00987 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. |