Anti-GTF2A2 Polyclonal Antibody
品牌：solarbio | 货号：K005388P
| 英文名称 | Anti-GTF2A2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HsT18745;T18745;TF2A2;TFIIA;TFIIA-12;TFIIA-gamma;TFIIAS |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 12kDa |
| Gene ID | 2958 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GTF2A2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GTF2A2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P52657 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]). |