Anti-H2AFY Polyclonal Antibody
品牌：solarbio | 货号：K004965P
| 英文名称 | Anti-H2AFY Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | H2A.y;H2A/y;H2AF12M;MACROH2A1.1;mH2A1;macroH2A1.2 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 40kDa |
| Gene ID | 9555 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human H2AFY |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human H2AFY |
| Subcellular Locations | Chromosome Nucleus |
| Swiss Prot | O75367 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. |