Anti-alpha-Synuclein Polyclonal Antibody
品牌：solarbio | 货号：K106539P
| 英文名称 | Anti-alpha-Synuclein Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NACP;PARK1;PARK4;PD1 |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 17kDa |
| Gene ID | 6622 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human alpha-Synuclein |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human alpha-Synuclein |
| Subcellular Locations | Cell junction Cytoplasm Membrane Nucleus Secreted cytosol synapse |
| Swiss Prot | P48061 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer’s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. |