Anti-TPX2 Polyclonal Antibody
品牌:solarbio | 货号:K007208P
| 英文名称 | Anti-TPX2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DIL2;p100;DIL-2;HCTP4;FLS353;HCA519;REPP86;C20orf1;C20orf2;GD:C20orf1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 86kDa |
| Gene ID | 22974 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TPX2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TPX2 |
| Subcellular Locations | Cytoplasm Cytoskeleton Microtubule Nucleus |
| Swiss Prot | Q9ULW0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.? |