Anti-PVRL4 Polyclonal Antibody
品牌:solarbio | 货号:K007119P
| 英文名称 | Anti-PVRL4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LNIR;PRR4;EDSS1;nectin-4 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-300. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 55kDa |
| Gene ID | 81607 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PVRL4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PVRL4 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q96NY8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. |