Anti-CD27 Polyclonal Antibody
品牌:solarbio | 货号:K106872P
| 英文名称 | Anti-CD27 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | S152;S152. LPFS2;T14;TNFRSF7;Tp55;S152.LPFS2;CD27 antigen |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 29kDa |
| Gene ID | 939 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CD27 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CD27 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P26842 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. |