Anti-NFKB2 Polyclonal Antibody
品牌:solarbio | 货号:K003592P
英文名称 |
Anti-NFKB2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
97kDa |
Gene ID |
4791 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human NFKB2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human NFKB2 |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
Q00653 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. |