Anti-LCP1 Polyclonal Antibody
品牌:solarbio | 货号:K004065P
| 英文名称 | Anti-LCP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CP64;HEL-S-37;L-PLASTIN;LC64P;LPL;PLS2 |
| 应用 | WB IP |
| 稀释比例 | WB 1:500-2000. IP 1:20-50. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 70kDa |
| Gene ID | 3936 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human LCP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human LCP1 |
| Subcellular Locations | Cell junction Cell projection Cytoplasm Cytoplasmic side Peripheral membrane protein cytoskeleton ruffle membrane |
| Swiss Prot | P13796 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. |