Anti-CAPN10 Polyclonal Antibody
品牌：solarbio | 货号：K006092P
| 英文名称 | Anti-CAPN10 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CANP10;NIDDM1 |
| 应用 | WB |
| 稀释比例 | WB 1:1000-4000. |
| 交叉反应 | Human |
| 蛋白分子量 | 75kDa |
| Gene ID | 11132 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CAPN10 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CAPN10 |
| Subcellular Locations | Cytosol Mitochondrion Plasma Membrane |
| Swiss Prot | Q9HC96 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. |