Anti-ABCB11 Polyclonal Antibody
品牌：solarbio | 货号：K005859P
| 英文名称 | Anti-ABCB11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ABC16;BRIC2;BSEP;PFIC-2;PFIC2;PGY4;SPGP |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 146kDa |
| Gene ID | 8647 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ABCB11 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ABCB11 |
| Subcellular Locations | Membrane Multi-pass membrane protein |
| Swiss Prot | O95342 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. |