Anti-TRPM8 Polyclonal Antibody
品牌：solarbio | 货号：K006331P
| 英文名称 | Anti-TRPM8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LTRPC6;TRPP8 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 128kDa |
| Gene ID | 79054 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TRPM8 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TRPM8 |
| Subcellular Locations | Cell membrane Endoplasmic reticulum membrane Membrane raft Multi-pass membrane protein |
| Swiss Prot | Q7Z2W7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. |