Anti-MVK Polyclonal Antibody
品牌：solarbio | 货号：K003933P
| 英文名称 | Anti-MVK Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LRBP;MK;MVLK;POROK3 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 42kDa |
| Gene ID | 4598 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MVK |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MVK |
| Subcellular Locations | Peroxisome |
| Swiss Prot | Q03426 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. |