Anti-F7 Polyclonal Antibody
品牌：solarbio | 货号：K008248P
| 英文名称 | Anti-F7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SPCA |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 49kDa |
| Gene ID | 2155 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human F7 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human F7 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P08709 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |