Anti-C8orf4 Polyclonal Antibody
品牌：solarbio | 货号：K004382P
| 英文名称 | Anti-C8orf4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TC-1;TC1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 12kDa |
| Gene ID | 56892 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human C8orf4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human C8orf4 |
| Subcellular Locations | Cytoplasm Nucleus Nucleus speckle nucleolus |
| Swiss Prot | Q9NR00 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. |