Anti-PTPRE Polyclonal Antibody
品牌：solarbio | 货号：K005089P
| 英文名称 | Anti-PTPRE Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HPTPE;PTPE;R-PTP-EPSILON |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 81kDa |
| Gene ID | 5791 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PTPRE |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PTPRE |
| Subcellular Locations | Cell membrane Cytoplasm Cytoplasm Single-pass type I membrane protein |
| Swiss Prot | P23469 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. |