Anti-CNTFR Polyclonal Antibody
品牌:solarbio | 货号:K003463P
英文名称 |
Anti-CNTFR Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CNTFR |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
41kDa |
Gene ID |
1271 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CNTFR |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CNTFR |
Subcellular Locations |
Cell membrane GPI-anchor Lipid-anchor |
Swiss Prot |
P26992 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. |