Anti-MIDN Polyclonal Antibody
品牌:solarbio | 货号:K007535P
| 英文名称 | Anti-MIDN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Midnolin |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 49kDa |
| Gene ID | 90007 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human MIDN |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human MIDN |
| Swiss Prot | Q504T8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Expression of the?midnolin?gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The?midnolin?encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the?midnolin?was studied by using?midnolin-green fluorescent protein (GFP) fusion proteins.?Midnolin?was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the?midnolin.?May be involved in regulation of genes related to neurogenesis in the nucleolus |