Anti-SOCS6 Polyclonal Antibody
品牌:solarbio | 货号:K006128P
| 英文名称 | Anti-SOCS6 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CIS-4;CIS4;HSPC060;SOCS-4;SOCS-6;SOCS4;SSI4;STAI4;STATI4 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 60kDa |
| Gene ID | 9306 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SOCS6 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SOCS6 |
| Subcellular Locations | Cytosol Plasma Membrane |
| Swiss Prot | O14544 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. |