Anti-CSE1L Polyclonal Antibody
品牌：solarbio | 货号：K006036P
| 英文名称 | Anti-CSE1L Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CAS;CSE1;XPO2 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 110kDa |
| Gene ID | 1434 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CSE1L |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CSE1L |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P55060 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. |