Anti-NDUFV1 Polyclonal Antibody
品牌:solarbio | 货号:K005622P
英文名称 |
Anti-NDUFV1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CI-51K;CI51KD;UQOR1 |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
51kDa |
Gene ID |
4723 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human NDUFV1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human NDUFV1 |
Subcellular Locations |
Mitochondrion |
Swiss Prot |
P49821 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson’s disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |