Anti-PLOD1 Polyclonal Antibody
品牌：solarbio | 货号：K005553P
| 英文名称 | Anti-PLOD1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EDS6;LH;LH1;LLH;PLOD |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 84kDa |
| Gene ID | 5351 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PLOD1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PLOD1 |
| Subcellular Locations | Lumenal side Peripheral membrane protein Rough endoplasmic reticulum membrane |
| Swiss Prot | Q02809 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. |