Anti-IL5 Polyclonal Antibody
品牌:solarbio | 货号:K005391P
| 英文名称 | Anti-IL5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EDF;IL-5;TRF |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 15kDa |
| Gene ID | 3567 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human IL5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human IL5 |
| Subcellular Locations | Secreted |
| Swiss Prot | P05113 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |