刀豆蛋白A(ConA),AF594标记

简要概述

产品基本信息

货号：25575

产品名称：刀豆蛋白A(ConA),AF594标记

规格：1mg

储存条件：-15℃避光防潮

保质期：12个月

产品物理化学光谱特性

Ex(nm)：499

Em(nm)：520

量子产率(cm ^-1 M ^-1)：73000

消光系数：0.92

产品介绍

刀豆蛋白A（ConA）是一种凝集素，可与各种糖，糖蛋白和糖脂中发现的某些结构特异性结合。ConA被广泛用于生物学和生物化学中，以表征各种细胞表面上的糖蛋白和其他含糖实体。它也可用于在凝集素亲和层析中纯化糖基化的大分子，以及研究各种免疫细胞的免疫调节。ConA在B-聚糖的分支结构的末端位置特异性结合α-D-甘露糖基和α-D-葡萄糖基残基（两个己糖，仅碳2上的醇不同）。它具有4个结合位点，对应于4个亚基。刀豆蛋白A（Con A）是细胞生物学中使用最广泛的凝集素之一。AF488标记的刀豆蛋白A（相当于Con A的AlexaFluor®488缀合物，AlexaFluor®是ThermoFisher的商标）。AlexaFluor®488 Con A选择性结合至a-甘露吡喃糖基和a-吡喃葡萄糖基残基。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的刀豆蛋白A,AF488标记。 

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参考文献

A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies.
Authors: Honkanen, Robert A and Huang, Liqun and Rigas, Basil
Journal: Journal of visualized experiments : JoVE (2020)

Acupuncture stimulation attenuates TNF-α production via vagal modulation in the concanavalin A model of hepatitis.
Authors: Lim, Hee-Don and Kim, Ki-Joong and Jo, Byung Gon and Park, Ji-Yeun and Namgung, Uk
Journal: Acupuncture in medicine : journal of the British Medical Acupuncture Society (2020): 964528420907338

Antioxidant Capacity and Hepatoprotective Role of Chitosan-Stabilized Selenium Nanoparticles in Concanavalin A-Induced Liver Injury in Mice.
Authors: Bai, Kaikai and Hong, Bihong and He, Jianlin and Huang, Wenwen
Journal: Nutrients (2020)

Concanavalin A Enhanced Proliferation and Osteogenic Differentiation of Dental Pulp Stem Cells.
Authors: Suardita, Ketut and Arundina, Ira and Tedjosasongko, Udijanto and Yuliati, Anita and Peeters, Harry Huiz and Wijaksana, I Komang Evan and Surboyo, Meircurius Dwi Condro
Journal: European journal of dentistry (2020): 123-127

Concanavalin A Toxicity Towards Potato Psyllid and Apoptosis Induction in Midgut Cells.
Authors: Tang, Xiao-Tian and Ibanez, Freddy and Tamborindeguy, Cecilia
Journal: Insects (2020)

Concanavalin A-Rose Bengal bioconjugate for targeted Gram-negative antimicrobial photodynamic therapy.
Authors: Cantelli, Andrea and Piro, Francesca and Pecchini, Pietro and Di Giosia, Matteo and Danielli, Alberto and Calvaresi, Matteo
Journal: Journal of photochemistry and photobiology. B, Biology (2020): 111852

Deficiency of O-linked-glycosylation regulates activation of T cells and aggravates Concanavalin A-induced liver injury.
Authors: Hao, Xiaohua and Gao, Meixin and He, Lingling and Ye, Xiaohui and Yang, Junru and Zhang, Fuyang and Liu, Ran and Wei, Hongshan
Journal: Toxicology (2020): 152411

Demethyleneberberine attenuates concanavalin A-induced autoimmune hepatitis in mice through inhibition of NF-κB and MAPK signaling.
Authors: Zhang, Miao and Li, Qingxia and Zhou, Cuisong and Zhao, Yaxing and Li, Ruiyan and Zhang, Yubin
Journal: International immunopharmacology (2020): 106137

Developmental exposure to low doses of dichlorodiphenyltrichloroethane impairs proliferative response of thymic lymphocytes to Concanavalin A in rats.
Authors: Yaglova, Nataliya V and Tsomartova, Elina S and Obernikhin, Sergey S and Ivanova, Marina Y and Chereshneva, Elizaveta V and Muhamedova, Svetlana G and Lomanovskaya, Tatiana A and Yaglov, Valentin V
Journal: Heliyon (2020): e03608

ISFET and Dex-AgNPs based portable sensor for reusable and real-time determinations of concanavalin A and glucose on smartphone.
Authors: Zhao, Shuang and Shi, Cong and Hu, Hongyang and Li, Zhengping and Xiao, Gang and Yang, Qiaochun and Sun, Peng and Cheng, Linyang and Niu, Wencheng and Bi, Jinshun and Yue, Zhao
Journal: Biosensors & bioelectronics (2020): 111962