产品简介：

该装置是专为研究利用小批量生产球形直径从200至1000微米左右的海藻酸钠珠而设置的。

该系统有一个电喷嘴连接地面。电极使喷嘴和硬化包膜之间产生静电场，它压迫微珠掉入包膜。一个泵(如注射泵)通过震动头产生一个稳定的液体流，使生产的小珠下降速度加快，它可以用肉眼观察。珠直径大小介于0.2和1毫米之间，偏差取决于物质的密度和表面张力。大概的估计，所收获的小珠是使用喷嘴直径的1.5至2倍，一般情况下，单个喷嘴每小时生产小珠10毫升，这取决于喷嘴直径、流量的变化、电压、喷嘴与硬化包膜之间的距离等，这些因素决定了珠子生成的大小。这种物理限制通过调节小喷嘴的直径和高粘度物质的压力来控制，当然你想要得到微珠的大小极大地影响了每个喷嘴的生产力。

三、供应范围：

1、可更换的喷嘴

2、电极/接管

3、带烧杯的磁力搅拌器

4、枪架与高压灭菌臂(高度可调)

5、废液管

6、电位可选的蠕动泵，调节范围0~100%

7、电位可选的搅拌速度，调节范围0~100%

8、电位可选的电极电压，调节范围0~10千伏

9、电压显示器

10、可打开的柜子（可放置注射泵）

11、高压开关

四、二款标配喷头（mm）    内径        外径

 可选配其它规格的喷头      0.17          0.35

                                               0.40          0.70

In most applications involving immobilisation of living cells or other biological materials the bead size needs to be small (<1 mm) and carefully controlled. The reason for this is mostly because of diffusion limitations of nutrients within hydrogel beads. A convenient way for production of small alginate beads in a controllable manner is the use of an electrostatic bead generator. The basic principle of the instrument is the use of an electrostatic force to pull droplets from a needle tip into a gelling bath. The Nisco instrument is designed for research uses production of smaller quantities of spherical alginate beads ranging in size from around 200 to 1000 μm.

The bead generator mainly consists of a high-voltage power supply (up to 7 kV), a switch for fine tuning of the voltage magnitude, an autoclavable needle holder, and a safety cage with an electrical safety switch. The alginate (or other) solution may be fed into the instrument from a syringe using a syringe pump. A magnet stirrer is built in underneath the gelling bath to keep the beads separated during gelling. Nozzles used in the instrument are made of steel, and are available in different diameters. The instrument is shipped with nozzles of 0.17 mm and 0.40 mm inner diameter. The instrument is capable of producing beads at rates up to 25‘000 capsules/min. The standard deviation of the bead diameters in one batch has been found to be around 3-6% on the average value. The bead generator has been used successfully in several studies involving immobilisation of living cells.

Bead size will be dependent of the following parameters: voltage and distance between the needle tip and the gelling bath, solution viscosity, flow rate of the solution as well as needle diameter. A suitable distance between the needle tip and the gelling bath for this instrument is around 10 mm. The appropriate bead size is selected by voltage adjustment. Bead diameter decreases with smaller needle diameters and increasing voltage.

To operate the unit, a syringe and syringe pump (or equivalent) is required (not included in scope of supply).

Included in scope of supply are:
? 2 nozzles (? 0.17 / 0.40)
? Beakers
? Magnetic stirrer
? Silicon hose

Options available:
? Syringe pump
? Peristaltic pump (for continous exchange of the hardening bath solution)
? Additional nozzles
? Additional arms (for several successive sterile bead productions).

PDF Download:

http://www.Jinpan.cn/downloads/products/nisco/Encapsulation1.pdf
http://www.Jinpan.cn/downloads/products/nisco/Encapsulation1.pdf
http://www.Jinpan.cn/downloads/products/nisco/Encapsulation3.pdf
微包囊科学论文和出版物下载

论文下载

Encapsulation Operation