SOS-ChromoTest kit, for rapid detection of genotoxicity or DNA damage.

Product No:5031

The SOS ChromoTest TM kit is based on a novel genetically engineered E.coli, which measures the primary response of a cell to genetic damage. In just a few hours, the kit provides a clear, completely objective measurement of the genotoxicity of a sample by a simple visual qualitative evaluation of the degree of DNA damage the cell experiences by observing the colour obtained. A more quantitative value may be obtained by spectrophotometry using a micro-plate reader. The SOS ChromoTest analyses are highly correlated with the Salmonella ‘Ames Test’ for certain materials.

Each kit contains all the reagents and disposable materials necessary to test at least four samples, including dilutions and controls.

A single SOS ChromoTest kit can be used for a total of 96 unit tests. These tests must include standards and controls (using at least 16 units). Thus, a single kit can screen 80 samples for yes/no responses.

For quantitative measurements, it is often necessary to allow for an adequate range of sample dilutions and replicates, thus testing five to ten samples with each kit. Below is an example plate used to detect the DNA damage when a genotoxic material is exposed to the SOS ChromoTest bacteria.

SOS Gene Response System

Potential applications of the SOS-ChromoTest that take advantage of the genetically engineered strain of E. coli, including testing of effluents for possible mutagenic or carcinogenic genotoxic compounds. It provides for an evaluation of potential genotoxicity, and is a convenient research tool

SOS显色试剂盒 SOS-ChromoTest Kit，用于快速检测遗传毒性或DNA损伤。

产品编号：5031

显色试验试剂盒是基于一种新的大肠杆菌基因工程，测量细胞遗传损伤的主要反应。在短短的几个小时，该试剂盒提供了一个清晰的，通过一个简单的视觉质量评价DNA损伤通过观察颜色获得的细胞体验度测量一个样本的遗传毒性完全客观的。

通过使用微板阅读器分光光度法，可以得到一个更定量的值。SOS显色试验分析与沙门氏菌的Ames试验对某些材料高度相关。
每个套件包含了所有必要的试剂测试至少四个样品和耗材，包括稀释和控制。
一个单一的SOS显色试剂盒可用于共96单元测试。

这些测试必须包括标准和控制（使用至少16个单位）。因此，一个单一的套件可以筛选80个样品是/没有反应。
定量测量，往往需要允许样品稀释和复制足够的范围，因此测试五至十份每盒。

下面是一个例子板用于检测DNA损伤时，毒性物质暴露于细菌的SOS显色试验。
SOS基因响应系统
潜在应用SOS显色试验，利用基因工程大肠杆菌菌株，包括可能的致突变或致癌基因毒性化合物废水的试验。它提供了潜在的遗传毒性的评价，是一种方便的研究工具。

SOS的染色体测试™试剂盒：在特别设计的大肠杆菌的基础上4小时微孔板遗传毒性生物学检测，96次测试，可做约5至10个样品。