Anti-UFD1L Polyclonal Antibody
英文名称 |
Anti-UFD1L Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
UFD1;UFD1L; |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
35kDa |
Gene ID |
7353 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human UFD1L |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human UFD1L |
Subcellular Locations |
Cytoplasm Nucleus cytosol |
Swiss Prot |
Q92890 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. |