Anti-Phospho-PDGFRA-Y754 Polyclonal Antibody
| 英文名称 | Anti-Phospho-PDGFRA-Y754 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD140A;PDGFR-2;PDGFR2 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 123kDa |
| Gene ID | 5156 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding Y754 of human PDGFRA |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding Y754 of human PDGFRA |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | P16234 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. |