Anti-CDH1 Polyclonal Antibody
品牌：solarbio | 货号：K003568P
| 英文名称 | Anti-CDH1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Arc-1;CD324;CDHE;ECAD;LCAM;UVO |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 97kDa |
| Gene ID | 999 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CDH1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CDH1 |
| Subcellular Locations | Cell junction Cell membrane Endosome Golgi apparatus Single-pass type I membrane protein trans-Golgi network |
| Swiss Prot | P12830 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. |