Anti-PGC Polyclonal Antibody
品牌：solarbio | 货号：K003487P
| 英文名称 | Anti-PGC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PEPC;PGII |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Mouse Rat |
| 蛋白分子量 | 42kDa |
| Gene ID | 5225 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human PGC |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human PGC |
| Subcellular Locations | Secreted |
| Swiss Prot | P20142 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. |