Anti-KCNA2 Polyclonal Antibody
品牌：solarbio | 货号：K004414P
| 英文名称 | Anti-KCNA2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EIEE32;HBK5;HK4;HUKIV;KV1.2;MK2;NGK1;RBK2 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 57kDa |
| Gene ID | 3737 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KCNA2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KCNA2 |
| Subcellular Locations | Cell junction Cell membrane Cell projection Endoplasmic reticulum membrane Membrane Multi-pass membrane protein axon dendrite lamellipodium membrane presynaptic cell membrane synapse synaptosome |
| Swiss Prot | P16389 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. |