Anti-IkB-α Polyclonal Antibody
品牌:solarbio | 货号:K008366P
英文名称 |
Anti-IkB-α Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
IKBA;MAD-3;NFKBI |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:15-50. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
36kDa |
Gene ID |
4792 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human NFKBIA |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human NFKBIA |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P25963 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.? |