Anti-PSMB10 Polyclonal Antibody
品牌：solarbio | 货号：K004003P
| 英文名称 | Anti-PSMB10 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LMP10;MECL1;beta2i |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 29kDa |
| Gene ID | 5699 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PSMB10 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PSMB10 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P40306 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. |