Anti-TMEM173 Polyclonal Antibody
品牌：solarbio | 货号：K003674P
| 英文名称 | Anti-TMEM173 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ERIS;MITA;MPYS;NET23;SAVI;STING;hMITA;hSTING |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 42kDa |
| Gene ID | 340061 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TMEM173 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TMEM173 |
| Subcellular Locations | Cell membrane Cytoplasm Endoplasmic reticulum membrane Mitochondrion outer membrane Multi-pass membrane protein perinuclear region |
| Swiss Prot | Q86WV6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |