Anti-LMP7 Polyclonal Antibody
品牌：solarbio | 货号：K107052P
| 英文名称 | Anti-LMP7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PSMB9,LMP2,PSMB6i,RING12,beta1i,proteasome subunit beta 9 |
| 应用 | IHC |
| 稀释比例 | IHC 1:100-300. |
| 蛋白分子量 | 23kDa |
| Gene ID | 5696 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human LMP7 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human LMP7 |
| Subcellular Locations | Nucleus Cytoplasm? |
| Swiss Prot | P28065 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. |