Anti-BAD Polyclonal Antibody
品牌：solarbio | 货号：K008075P
| 英文名称 | Anti-BAD Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BBC2;BCL2L8 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 18kDa |
| Gene ID | 572 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human BAD |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human BAD |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q92934 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |