Anti-GPI Polyclonal Antibody
品牌：solarbio | 货号：K004864P
| 英文名称 | Anti-GPI Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AMF;GNPI;NLK;PGI;PHI;SA-36;SA36 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 63kDa |
| Gene ID | 2821 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GPI |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GPI |
| Subcellular Locations | Cytoplasm Secreted |
| Swiss Prot | P06744 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. |