Anti-SLC6A4 Polyclonal Antibody
品牌:solarbio | 货号:K106831P
| 英文名称 | Anti-SLC6A4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | 5-HTT;5-HTTLPR;5HTT;HTT;OCD1;SERT;SERT1;hSERT;solute carrier family 6 member 4 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 70kDa |
| Gene ID | 6532 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human SLC6A4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human SLC6A4 |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P31645 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. |