Anti-KIFAP3 Polyclonal Antibody
品牌：solarbio | 货号：K003817P
| 英文名称 | Anti-KIFAP3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FLA3;KAP-1;KAP-3;KAP3;SMAP;Smg-GDS;dJ190I16.1 |
| 应用 | WB IP |
| 稀释比例 | WB 1:500-2000. IP 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 91kDa |
| Gene ID | 22920 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KIFAP3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KIFAP3 |
| Subcellular Locations | Cytoskeleton Cytosol Plasma Membrane Endoplasmic reticulum Golgi apparatus Nucleus |
| Swiss Prot | Q92845 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 ‘Armadillo’ repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. |